I'd try antonis's suggestion, it is a quick test. If that does nothing, I'd then use my audio probe to see where the signal degrades (after removing that jumper).
While playing a note, Audio Probe Collector of Q1...base and collector of Q2. Somewhere in there the signal should go from 'normal' sounding to crap, that may tell something. Voltage at Q3 collector is 4.03, close to the nominal 4.5V, so bias could make it SOUND a little off, but it seems that it should WORK at this point, barring a bad connection or bad part, etc. Even better, try to dial that to 4.5 with the pot before probing, if you can. Don't short out anything while you probe
There could be a solder bridge or cold solder joint making a bad contact, for one thing. Since you do have signal at output, it's probably nothing huge, just that you have to find it!