Hi everyone, round two!

I've tried to add everyone's suggestions, so please point out anything I missed or stuck in the wrong place.
I could be wildly mistaken, but I think the LM7805 needs a few caps attached to make it function as a regulator per the datasheet?

I think you could be wildly correct

Thank you for reminding me that drawing layouts at midnight is not the best plan I ever had!
I knew Moid would have a go at it! Ah, the universe turns in its expected order.
Wow, I had no idea that I had that level of reliability

Sadly it won't last, work is picking up for me now and will be stupidly crazy until Christmas, which means my chances of fixing that Sentinel Reverb are looking slim... but I haven't forgotten it!
The output cap shouldn't go to 0v though, and you don't need that r/h long link.
If you cut the track below pin 9 (K8) then move the 1M pull-down to the bottom track bridging that track cut (K7-K9), the output wire also moves down to the bottom track (K14). The polarity of the output cap is negative to the bottom trace.
If you make the long link under the chip in 3 pieces, it can call in at pins 3 & 4 and you don't need the 2 links on the left.
This is a noise machine, so noise and audio quality are not on the agenda. All the nF value caps can be cheap ceramic discs or mlcc as they can better fit over adjacent tracks.
Any constant supply noise/hum from a less than perfect PSU might be objectionable. Another 100uF cap between the top 2 tracks would deal with that.
Thanks anotherjim. I've incorporated all your suggestions (I think). Would you mind checking I put them in the right places please?
moidy, you have a DC bypass cap, we want a DC blocking cap - they go in series with signal. 100uF is probably way too much, maybe 100nF would suffice from all the screeching sounds in the clip. and 1M could be 100k, or an A100k or A50k pot. all this will become clear once you breadboard it, tho.
Well luckily my head is still screwed on or I'd forget that too! Thanks Duck - I've changed those values you suggested too. Haven't added the pot yet, because I'm not sure if spectreman wants that. Spectreman, let me know if you want another pot; I'm not sure what it will do, but Duck knows his stuff so it'll probably something fun.
Amazing! I'm super amped that you all are into this! Thanks for all the input & work (thanks moid, for the initial layout!). I'm excited for the future posts...looks like we're getting real close to a working layout. Awesome!
That's no problem, this does sound like something I'd like to build at some point and I would do it on vero anyway. It's doubtful I'll get the chance to make this until Christmas though

So if you build it I would like to know if it works. It does sound like you should probably breadboard this first if John's comments are anything to go by.
In my experience with this circuit (as drawn) I get almost none of
the sounds in the video. Shorting pin 16 to 15,9,10 briefly, not all at once
but randomly glitches the repeat to get some of the sounds though.
It's hit or miss depending on the knob setting. Wildly variable and unpredictable...
I wonder if the missing IC3 is actually an opamp or other IC (a PLL?) that generates a loud tone to feed into the PT2399 to get it oscillating? So it might work without it, but not very well as you have found? I wonder if just piping guitar audio into pin 16 might be enough?